Molecular Biology Computer Programs

GENECONV (Statistical Tests for Detecting Gene Conversion) - Version 1.81a

Given an alignment of DNA or protein sequences, GENECONV finds the most likely candidates for aligned gene conversion events between pairs of sequences in the alignment, as well as the most likely candidates for a gene conversion events from outside of the alignment. Candidate events are ranked by multiple-comparison corrected P-values and listed in a spreadsheet-like output file.

Provisions can be made for mismatches with a mismatch penalty. As a program option, sequences near the endpoints of candidate events can also be listed. Searches can be restricted to within-group gene conversion events only, which leads to more powerful multiple comparison procedures.

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Stanley Sawyer
Department of Mathematics
Washington University in St. Louis
St. Louis, Missouri 63130, USA

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Both programs are free for academic use.

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    Last modified October 11, 2009