Mathematical genetics, probability, statistics
Honors, Editorial Boards, Etc:Fellow, Institute of Mathematical Statistics
Editorial Advisory Board,
Molecular Biology and Evolution (2000-2008)
Associate Editor, Annals of Applied Probability (2006)
Deputy Editor for online publishing,
Molecular Biology and Evolution (2000-2002)
Associate Editor, Molecular Biology and Evolution (1994-2000)
Probability Editor, Proceedings of the American Mathematical Society
Associate Editor, Annals of Probability (1979-1985, 1991-1994)
NIH Genetics and GVE Study Sections, ad hoc (1991, 1998-2007)
NSF panels in probability and biology (2000, 2002)
Molecular Biology Computer Program
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Some Representative Recent Publications:
Amei, Amei, and Stanley A. Sawyer (2012) Statistical inference of
selection and divergence from a time-dependent poisson random field
model. PLoS ONE 7 (4), doi:10.1371/journal.pone.0034413
Leopold, Shana R., Stanley A. Sawyer, Thomas S. Whittam, and Phillip I.
Tarr (2011) Obscured phylogeny and recombinational dormancy in
Escherichia coli. BMC Evolutionary Biology 11, 183.
Amei, Amei, and Stanley A. Sawyer (2010) A time-dependent Poisson
random field model for polymorphism within and between two related
biological species. Annals of Applied Probability 20, 1663--1696.
Leopold Shana R, Magrini V, ..., Mardis Elaine R, ..., Sawyer Stanley A,
Whittam Thomas S, and Tarr Phillip I (2009) A precise reconstruction of
the emergence and constrained radiations of Escherichia coli O157
portrayed by backbone concatenomic analysis. Proceedings of the National
Academy of Sciences USA Vol.106, 8713-8718.
Sawyer, Stanley A, John Parsch, Zhi Zyhang, and Daniel L Hartl
(2007) Prevalence of positive selection among nearly neutral amino acid
replacements in Drosophila. Proceedings of the National Academy of
Sciences USA Vol.104, 6504-6510.
How can one tell in which direction evolution is going?
(A nontechnical description of the motivation behind the previous paper.
This was written for the
Web site of someone who was nice enough to provide access to
a microprocessor array when I was on sabbatical in 2002.)
Butler, Marguerite, Stanley A. Sawyer, and Jonathan Losos (2007) Sexual
dimorphism is an agent for increased morphological diversity in an
adaptive radiation. Nature Vol.447, May 10 issue, 202-205.
Fauquet, C. M., S. Sawyer, A. M. Idris, and J. K. Brown (2005) Sequence
analysis and classification of apparent recombinant begomoviruses
infecting tomato in the Nile and Mediterranean Basins. Phytopathology
Volkman, Sarah K., Elena Lozovsky, Alyssa E. Barry, Trevor Bedford, Lara
Bethke, Alissa Myrick, Karen P. Day, Daniel L. Hartl, Dyann F. Wirth, and
Stanley A. Sawyer (2007) Genomic heterogeneity in the density of noncoding
single-nucleotide and microsatellite polymorphisms in Plasmodium
falciparum. Gene Vol.387, 1-6.
Piccirillo, Jay F., Edward L. Spitznagel, Anna Vlahiotis, and S. A. Sawyer
(2006) Development of Prognostigram: A cancer patient-specific prognostic
program. (Survival curves influenced by high blood pressure, other
diseases, etc.) Manuscript.
Sawyer, S A, R J Kulathinal, C D Bustamante, and D L Hartl (2003)
Bayesian analysis suggests that most amino acid replacements in
Drosophila are driven by positive selection. Journal of Molecular
Evolution 57, S154-S164.
Talk (PDF file)
Bustamante, C D, R Nielsen, S A Sawyer, K M Olsen, M D Purugganan, and D
L Hartl (2002) The cost of inbreeding in Arabidopsis. Nature 416,
Rich, S M, S A Sawyer, and A G Barbour (2001) Antigen polymorphism in
Borrelia hermsii, a clonal pathogenic bacterium. Proceedings of
the National Academy of Sciences USA 98, pp15038-15043.
Bustamante, C D, J Wakeley, S A Sawyer, and D L Hartl (2001) Directional
selection and the site-frequency spectrum. Genetics 159, pp1779-1788.
Hartl, D L, E F Boyd, C D Bustamente, and S A Sawyer (2000) The glean
machine: What can we learn from DNA sequence polymorphisms? In
S. Suhai (Ed.), Genomics and proteomics, Kluwer Academic / Plenum
Publishers, New York, pp37-49.
Padidam, M, S A Sawyer, and C Fauquet (1999) Possible emergence of new
geminiviruses by frequent recombination. Virology 265, pp218-225.
S A Sawyer (1997) Estimating selection and mutation rates from a random
field model for polymorphic sites. In P. Donnelly and S. Tavare
(Eds.), Progress in population genetics and human evolution, IMA Volumes
in Mathematics and its Applications 87, Springer-Verlag, New York, 1997,
S A Sawyer (1997) Martin boundaries and random walks. In Adam
Koranyi (Ed.), Harmonic functions on trees and buildings. Contemporary
Mathematics 206, American Mathematical Society, Providence, pp17-44.
Some Older Publications:
Kapur, V, S Kanjilal, M R Hamrick, L-L Li, T S Whitham, S A Sawyer, and J
M Musser (1995) Molecular population genetic analysis of the
streptokinase gene of Streptococcus pyogenes: mosaic alleles
generated by recombination. Molecular Microbiology 16, pp509-519.
S A Sawyer (1994) Inferring selection and mutation from DNA sequences:
The McDonald-Kreitman test revisited. In G. B. Golding (Ed.)
Non-Neutral Evolution: Theories and Molecular Data. Chapman and Hall,
Hartl, D L, Etsuko Moriyama, and S A Sawyer (1994) Selection intensity
for codon bias. Genetics 138, pp227-234.
Phillips, O, Alwyn Gentry, P Hall, S A Sawyer, and R. Vasquez (1994)
Dynamics and species-richness of tropical rain forests. Proceedings of
the National Academy of Sciences USA 91, pp2805-2809.
Sawyer, S A, and D L Hartl (1992) Population genetics of polymorphism and
divergence. Genetics 132, pp1161-1176.
Palazzolo, M, S A Sawyer, C Martin, D Smoller, and D. L. Hartl (1991)
Optimized strategies for sequence-tagged-site selection in genome
mapping. Proceedings of the National Academy of Sciences of the USA 88
Sawyer, S A (1990) Maximum likelihood estimators for incorrect models,
with an application to ascertainment bias for continuous characters.
Theoretical Population Biology 38, pp351-366.
Sawyer, S A (1989) Statistical tests for detecting gene conversion.
Molecular Biology and Evolution 6, pp526-538.
Sawyer, S A, D E Dykhuizen, R DuBose, L Green, T Mutangadura-Mhlanga, D
Wolczyk, and D. L. Hartl (1987) Distribution and abundance of insertion
sequences among natural isolates of Escherichia coli. Genetics 115,
Some Older Publications Yet:
Sawyer, S A (1979) A limit theorem for patch sizes in a
selectively-neutral migration model. Jour. Applied Probability 16,
Sawyer, S A, and J Fleischman (1979) Maximum geographic range of a mutant
allele considered as a sub-type of a Brownian branching random field.
Proceedings of the National Academy of Sciences USA 76, pp872-875.
Sawyer, S A (1976) Branching diffusion processes in population genetics.
Adv. Applied Probability 8, pp659-689.
Sawyer, S A (1977) On the past history of an allele now known to have
frequency p. Jour. Applied Probability 14, pp439-450.
Sawyer, S A (1974) A Fatou theorem for the general one-dimensional
parabolic equation. Indiana Univ. Math. Jour. 24, 451-498.
Books:A TeX Primer for Scientists, Stanley Sawyer and Steven Krantz,
CRC Press, Boca Raton, FL (1995, 399+viii pgs.)
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Last modified August 11, 2013